Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency.

نویسندگان

  • Akifumi Endo
  • Ken Watanabe
  • Tamae Ohye
  • Kyoko Suzuki
  • Tomoyo Matsubara
  • Norio Shimizu
  • Hiroki Kurahashi
  • Tetsushi Yoshikawa
  • Harutaka Katano
  • Naoki Inoue
  • Kohsuke Imai
  • Masatoshi Takagi
  • Tomohiro Morio
  • Shuki Mizutani
چکیده

It has been unclear whether chromosomally integrated human herpesvirus 6 (ciHHV-6) can be activated with pathogenic effects on the human body. We present molecular and virological evidence of ciHHV-6A activation in a patient with X-linked severe combined immunodeficiency. These findings have significant implications for the management of patients with ciHHV-6.

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 59 4  شماره 

صفحات  -

تاریخ انتشار 2014